ag nanoparticle/melamine sulfonic acid supported on silica gel as an efficient catalytic system for synthesis of dihydropyrimidin thiones

نویسندگان

parya nasehi

alireza kiasat

mohammad kazem mohammadi

چکیده

3,4-dihydropyrimidin-2(1h)-thiones were synthesized in the presence of ag nanoparticle/melamine sulfonic acid (msa) supported on silica gel. the reaction was carried out at 110 oc for 20 min under solvent free conditions. in all cases, the three component reaction proceeded smoothly to give the corresponding 3,4-dihydropyrimidin-2(1h)-thiones in moderate to good yield. we have found the best conditions are using 0.2 g msa, 0.05 g ag nanoparticle.sio2 under solvent free conditions at 110 oc. this method have some advantages such as good yield, mild reaction conditions, ease of operation and work up, short reaction time and high product purity. in this work, we have investigated the application of ag nanoparticle/msa.sio2 for synthesis of biginelli – type condensation.

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Ag nanoparticle/melamine sulfonic acid supported on silica gel as an efficient catalytic system for synthesis of dihydropyrimidin thiones

3,4-dihydropyrimidin-2(1H)-thiones were synthesized in the presence of Ag nanoparticle/melamine sulfonic acid (MSA) supported on silica gel. The reaction was carried out at 110 oC for 20 min under solvent free conditions. In all cases, the three component reaction proceeded smoothly to give the corresponding 3,4-dihydropyrimidin-2(1H)-thiones in moderate to good yield. We have found the best co...

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Nano-silica supported ethane-sulfonic acid: An efficient heterogeneous solid acid catalyst for one-pot synthesis of xanthene and acridine derivatives

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عنوان ژورنال:
iranian chemical communication

ناشر: payame noor university (pnu)

ISSN 2423-4958

دوره 2

شماره Issue 3 (pp. 162-231) 2014

کلمات کلیدی
[ ' n a n o p a r t i c l e m e l a m i n e s u l f o n i c a c i d . s i o 2 ' , ' b i g i n e l l i r e a c t i o n ' , 3 , 4 , ' d i h y d r o p y r i m i d i n ' , ' 2 ( 1 h ) ' , ' t h i o n e ' , ' s o l v e n t f r e e ' ]

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